The project proposes to turn to the past to apprehend the future better to unravel the true scale and the functional evolutionary mechanisms of the long-term battle between bats and viruses: by detecting ancient epidemics through bat genomic adaptation and molecular virology to identify virus families with a pathogenic potential and to unravel innovation in bat genomes that may be key for antiviral prevention/therapeutics. 

Uveal melanoma (UM) is the most common primary intraocular malignancy in adults with different prognostics. Standard of care
carries side effects with long-term morbidities, including blindness. There is an unmet need for therapies protecting ocular tissues
and preserving vision. This project will address this challenge by combining near-infrared photo-controlled gene-based therapeutic
delivery with photonic nanomaterials to investigate focused gene therapy efficacy against UM using a new organoids-on-chip model.

This study aims to understand how natural pore-forming peptides kill pathogens to develop new therapeutic antimicrobial strategies, funded by the France-Arizona Institute for Global Grand Challenges

Ion channels are expressed in many tissues. Due to their important roles, they constitute one of the most important drug targets for the treatment of diseases such as type-2 diabetes, epilepsy, pain and cardiac arrhythmias. We and others demonstrated that peptides from venoms are promising tools can selectively target ion channels.