Image Molecular and functional genomics of ancient viral epidemics The project proposes to turn to the past to apprehend the future better to unravel the true scale and the functional evolutionary mechanisms of the long-term battle between bats and viruses: by detecting ancient epidemics through bat genomic adaptation and molecular virology to identify virus families with a pathogenic potential and to unravel innovation in bat genomes that may be key for antiviral prevention/therapeutics. Read more Image Study of therapeutic effects of 2-photons controlled gene delivery with nanoparticles in uveal melanoma using organoids-on-chip model. Uveal melanoma (UM) is the most common primary intraocular malignancy in adults with different prognostics. Standard of care carries side effects with long-term morbidities, including blindness. There is an unmet need for therapies protecting ocular tissues and preserving vision. This project will address this challenge by combining near-infrared photo-controlled gene-based therapeutic delivery with photonic nanomaterials to investigate focused gene therapy efficacy against UM using a new organoids-on-chip model. Read more Image Tackling Infectious Disease by Understanding Pore-Forming Peptides Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Read more
Image Molecular and functional genomics of ancient viral epidemics The project proposes to turn to the past to apprehend the future better to unravel the true scale and the functional evolutionary mechanisms of the long-term battle between bats and viruses: by detecting ancient epidemics through bat genomic adaptation and molecular virology to identify virus families with a pathogenic potential and to unravel innovation in bat genomes that may be key for antiviral prevention/therapeutics. Read more
Image Study of therapeutic effects of 2-photons controlled gene delivery with nanoparticles in uveal melanoma using organoids-on-chip model. Uveal melanoma (UM) is the most common primary intraocular malignancy in adults with different prognostics. Standard of care carries side effects with long-term morbidities, including blindness. There is an unmet need for therapies protecting ocular tissues and preserving vision. This project will address this challenge by combining near-infrared photo-controlled gene-based therapeutic delivery with photonic nanomaterials to investigate focused gene therapy efficacy against UM using a new organoids-on-chip model. Read more
Image Tackling Infectious Disease by Understanding Pore-Forming Peptides Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Read more
